Over the years, medical science has been continuously evolving to accommodate any changes in the medical landscape. It does not cease from looking for solutions and treatments of various diseases. The discovery of liposome is among the most remarkable breakthroughs in the industry. This is used to aid drug intake to enhance its efficiency, increase success rate in organ transplant surgery and treat several medical malfunctions.
Liposomes are microscopical vesicles developed in an artificial environment like a laboratory. These are composed of phospholipids that are naturally produced or extracted from another source. Its outer wall has similar composition to that of a cell wall. This allows direct interaction between the cells and the liposomes. These tiny, spheroid-shaped bubbles are typically watery in its core.
This structure is most popular for its function to help in drug administration. With its unique property, the vesicles can deliver the drugs to specific parts of the patient's body using the process of diffusion. This property is essential in transporting biological agents, such as antibodies, to specific tissues. Its bi-layered membranes also allow carriage of hydrophobic drugs.
Furthermore, this helps extend the transfer time of the medicines. The double-layered spheres slowly transmits the drugs in interval for a period of time so the body can take it in gradually. This and the ability to direct its target make this a perfect choice in reducing the medicines' side-effects and enhance its potency.
The structure is considered a natural treatment to cancer, too. The vesicle has the ability to target cancer cells. It can also slip right into the tumor by following the blood flow. Liposomes are small in size, so it does not stray away from the bloodstream. Not to mention its composition that is closely similar to blood vessels, which are trapped inside the endothelial wall. In contrast, cancer cells are leaky in nature. It lets through even the small particles to escape.
This can also help fight autoimmune diseases. In most transplant surgeries, the body initially identifies the newly transplanted organ as a foreign object. As a result, the immune system will try to attack it as the body's natural reaction to protect itself from infestation. This can lead to the body's rejection of the harvested organ. The artificial lipid can help suppress the immune system to slow down its progression.
The vesicles are not spontaneously produced, though. There are various methods used to create these drug vessels according to its function and purpose. Its method of dissemination must be considered as well as the type of materials that will be transported.
The vesicles are produced in different sizes. Generally, these have to be small enough for the white blood cells to engulf the bubbles with ease before releasing the drugs it carries. A decision must be made before the production process to determine the size and number of vessels needed. Reproduction must also be anticipated.
If there is one thing that could hold back medical experts from using liposome, it would be the production expenses. At present, mass production is not feasible since the vessels may not last after it has been produced. There were instances of unintentional mixing of drugs and cases of instability as well. Other than that, nobody can argue of the wonderful benefits this breakthrough promises.
Liposomes are microscopical vesicles developed in an artificial environment like a laboratory. These are composed of phospholipids that are naturally produced or extracted from another source. Its outer wall has similar composition to that of a cell wall. This allows direct interaction between the cells and the liposomes. These tiny, spheroid-shaped bubbles are typically watery in its core.
This structure is most popular for its function to help in drug administration. With its unique property, the vesicles can deliver the drugs to specific parts of the patient's body using the process of diffusion. This property is essential in transporting biological agents, such as antibodies, to specific tissues. Its bi-layered membranes also allow carriage of hydrophobic drugs.
Furthermore, this helps extend the transfer time of the medicines. The double-layered spheres slowly transmits the drugs in interval for a period of time so the body can take it in gradually. This and the ability to direct its target make this a perfect choice in reducing the medicines' side-effects and enhance its potency.
The structure is considered a natural treatment to cancer, too. The vesicle has the ability to target cancer cells. It can also slip right into the tumor by following the blood flow. Liposomes are small in size, so it does not stray away from the bloodstream. Not to mention its composition that is closely similar to blood vessels, which are trapped inside the endothelial wall. In contrast, cancer cells are leaky in nature. It lets through even the small particles to escape.
This can also help fight autoimmune diseases. In most transplant surgeries, the body initially identifies the newly transplanted organ as a foreign object. As a result, the immune system will try to attack it as the body's natural reaction to protect itself from infestation. This can lead to the body's rejection of the harvested organ. The artificial lipid can help suppress the immune system to slow down its progression.
The vesicles are not spontaneously produced, though. There are various methods used to create these drug vessels according to its function and purpose. Its method of dissemination must be considered as well as the type of materials that will be transported.
The vesicles are produced in different sizes. Generally, these have to be small enough for the white blood cells to engulf the bubbles with ease before releasing the drugs it carries. A decision must be made before the production process to determine the size and number of vessels needed. Reproduction must also be anticipated.
If there is one thing that could hold back medical experts from using liposome, it would be the production expenses. At present, mass production is not feasible since the vessels may not last after it has been produced. There were instances of unintentional mixing of drugs and cases of instability as well. Other than that, nobody can argue of the wonderful benefits this breakthrough promises.
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